Drexel

We’re hiring a postdoc!

neuronDescription: This position is for a post-doctoral researcher with extensive experience in neurobiology, neuroimmune pharmacology, and translational neuroscience eager to contribute to the overall mission of the lab with creativity and passion. This individual will be involved in ongoing NIH-funded projects in the field of neuroHIV, neuroprotection, and drug abuse, which require expertise in both cellular/molecular neurobiology techniques and small animal in vivo models. The experienced researcher is expected to facilitate teamwork, participate in the training of graduate students, and ultimately enhance the research potential of the whole group.

 

Qualifications: PhD (or MD/PhD) or equivalent doctoral degree is required.

At least 3 years’ experience in a neurobiology or translational neuroscience setting.

Strong communication and interpersonal skills.

Time management and organization skills.two neuron

Highest work ethic standards.

 

Candidates should have extensive experience in traditional and modern techniques of cellular and molecular neurobiology, histology, microscopy/cellular imaging, and use of small animal models to study CNS disorders. Ideal candidates will have experience in techniques including electrophysiology, multi-electrode arrays, and/or in vivo imaging. Candidates will be able to keep up with, and implement, the many emerging technical innovations in the field of neuroscience. Previous experience in the field of HIV-associated neurocognitive disorders is a plus, along with familiarity with primary neuronal cultures and brain tissue processing, self-motivation, commitment to success and innovation, and exceptional organization and communication skills.  Opportunities for career advancement are available.

 

Contact: Please contact Dr. Olimpia Meucci (om29@drexel.edu) for additional information.

NIDA

MERIT award extension

We received a five-year extension of our R37 MERIT (method to extend research in time) award from the National Institute on Drug Abuse! The extension will support lab’s longtime research project “Role of chemokines in neuronal function and survival.”

Eri D

Erica Dalla defends PhD thesis!

Eri DCongratulations to former lab member Erica Dalla, who successfully defended her PhD thesis at Mount Sinai Icahn School of Medicine!

Erica worked in the lab of Dr. Julio Aguirre-Ghiso where she studied how lung macrophages control the fate of disseminated tumor cells. Her work in the PhD program contributed to several high-profile publications that capped off a highly productive period of research!

Happy Holidays from the Meucci Lab!

Meucci lab members

Jared Luchetta

Jared Luchetta presented for the joint NIMH center seminar series

Jared was invited to present his research this month as a part of the 2021-2022 Joint National Institute of Mental Health (NIMH) center seminar series! Jared discussed his most recent work in a talk titled: Examining how CXCL12 affects structural plasticity and cortical network function. The seminar series is organized by the NIMH administrative core at Johns Hopkins University, who also host previous talks from the series on their website.

Dr. Irollo promoted to Research Assistant Professor

This month, Dr. Elena Irollo enjoyed two outstanding events. She was promoted to a new position as a Research Assistant Professor in the department, and more importantly, she has tied the knot with her husband. Congratulations, Elena & Jonathan!

Elena Irollo

Meucci and Gaskill labs publish a collaborative review article

graphical abstract

Graphical abstract

Dr. Meucci and her former student Dr. Lindsay Festa collaborated with Dr. Gaskill and his former student Dr. Emily Nickoloff on a new review article discussing how HIV co-receptor signaling can contribute to HIV pathogenesis. The review article starts with a primer on HIV pathogenesis and the chemokine co-receptors that HIV uses to infect cells, and then thoroughly explores the signaling pathways downstream of HIV-activated co-receptors and how these pathways can contribute to HIV neuropathogenesis. The article ends with a discussion of treatment strategies based on targeting HIV co-receptors and their downstream signaling pathways.

The article is titled “Co-receptor signaling in the pathogenesis of neuroHIV” and is open-access and freely available in the journal Retrovirology.

 

cxcl12

Meucci lab publishes review on neuronal dysfunction in HAND

Simplified pathways that can contribute to dendritic spine deficits in HAND (left) and pathways that counteract these effects (right).

In a new review article published in Cellular and Molecular Life Sciences, Dr. Meucci’s group discusses clinical evidence of disrupted neuronal connectivity in HIV patients and the molecular mechanisms that drive neuronal dysfunction and cognitive impairment in HIV-associated neurocognitive disorders.

The article is titled “Mechanisms of neuronal dysfunction in HIV-associated neurocognitive disorders” and is freely available here. For the PDF version, click here.

XJared

Jared Luchetta awarded neuroAIDS fellowship

Jared LuchettaJared Luchetta was appointed as a National Research Service Award (NRSA) pre-doctoral fellow on Drexel University’s Interdisciplinary and Translational Research Training Grant in NeuroAIDS. The training grant is funded by the National Institute of Mental Health as part of a long-standing collaboration between Drexel and Temple University investigators.

Congratulations Jared!