New publication on opioid control of iron transport
Dr. Elena Irollo and colleagues from the Meucci lab recently published a new study on how morphine uses the iron transporter divalent metal transporter 1 (DMT1) to control iron metabolism in cortical neurons. The study also reports a new set of molecular tools to study DMT1 in a variety of cellular systems. This work continues a longstanding story on how morphine and mu-opioid agonists can impair cognitive function in people with HIV by dysregulating neuronal iron metabolism.
The study is open access and freely available at the Journal of Neuroimmune Pharmacology.