Dr. Meucci and her former student Dr. Lindsay Festa collaborated with Dr. Gaskill and his former student Dr. Emily Nickoloff on a new review article discussing how HIV co-receptor signaling can contribute to HIV pathogenesis. The review article starts with a primer on HIV pathogenesis and the chemokine co-receptors that HIV uses to infect cells, and then thoroughly explores the signaling pathways downstream of HIV-activated co-receptors and how these pathways can contribute to HIV neuropathogenesis. The article ends with a discussion of treatment strategies based on targeting HIV co-receptors and their downstream signaling pathways.

The article is titled “Co-receptor signaling in the pathogenesis of neuroHIV” and is open-access and freely available in the journal Retrovirology.